Among the cancers studied in relation to PFAS exposure, testicular cancer carries some of the most direct and specific scientific findings. The International Agency for Research on Cancer's 2023 classification of PFOA as a Group 1 human carcinogen cited testicular cancer as one of the primary cancer sites in its epidemiologic evidence review, placing it alongside kidney cancer as a central basis for that determination.
Claim ApplicationUnlike many occupational carcinogens that damage DNA directly, PFAS drive testicular cancer through a hormonal pathway. In addition to disturbing testosterone signaling and the balance of reproductive hormones, PFAS compounds interfere with immune regulation and gene expression in ways that lead to abnormal cellular growth.
PFAS compounds accumulate in blood serum and persist for years after external exposure ends, meaning internal exposure continues long after a worker leaves the contaminated environment. The C8 Science Panel found a probable link between PFOA exposure and testicular cancer, one of only a handful of diseases to meet that standard, and a quantitative meta-analysis found approximately a 3% increased risk per 10 ng/mL increase in serum PFOA.
Firefighting foam used in training exercises and emergency derailment response, and contaminated groundwater near rail yards and maintenance facilities are potential sources of PFAS exposure for railroad workers.
Testicular cancer due to occupational PFAS exposure may be eligible for FELA compensation, including medical expenses, lost income, and pain and suffering. The science linking PFOA to testicular cancer is among the stronger findings in PFAS litigation, giving railroad workers a well-documented foundation for a claim. Contact ELG Law today to have your occupational history and diagnosis reviewed by a team with 35 years of railroad exposure experience.