PFAS chemicals PFHxS and PFUnDA linked to pancreatic cancer

By Michael Bartlett on May 29th, 2025 in

Unexplained abdominal discomfort that persists for weeks might seem like a minor issue. However, individuals with a history of PFAS exposure should take these symptoms more seriously. It has been shown that chemicals like PFHxS and PFUnDA may increase the risk of pancreatic cancer, making routine abdominal pain a potentially significant warning sign.

Most cases of pancreatic cancer are detected only after they have advanced to later stages, making it the fourth leading cause of cancer deaths in the country. Those exposed to hazardous chemicals such as PFAS during military service or contaminated water systems should be aware of their symptoms.

Certain symptoms need immediate attention, particularly for individuals with documented chemical exposure history:

  • Severe abdominal pain that spreads to the back
  • Unintended weight loss and loss of appetite
  • Jaundice
  • Sudden-onset diabetes
  • Extreme fatigue or physical weakness
  • Dark-colored urine
  • Deep vein thrombosis or blood clots
  • Persistent nausea and vomiting

Scientific evidence connects PFHxS and PFUnDA to pancreatic cancer development

Groundbreaking research conducted by medical institutions analyzed blood samples from both pancreatic cancer patients and healthy control groups. The investigation revealed alarming correlations between specific PFAS chemicals and cancer occurrence. Scientists examine multiple PFAS compounds in blood serum using sophisticated analytical methods.

The findings show that perfluoroundecanoic acid (PFUnDA) presented the strongest cancer association. People with elevated PFUnDA concentrations faced significantly higher pancreatic cancer rates compared to those with minimal levels. There was an increased risk associated with PFUnDA and PFHxS in the study population.

These manufactured chemicals interfere with the normal function of cells, compromising biological systems. PFAS compounds alter gene expression patterns and cause harmful oxidative damage to the body. The continuous damage to cells eventually results in pancreatic cancer.

Who is at risk of pancreatic cancer from PFAS exposure?

PFAS contamination spreads throughout communities due to multiple sources of exposure. Materials containing PFAS are widely used on military bases, airports, and manufacturing facilities, causing widespread environmental pollution. Health surveillance data reveal that most American adults carry detectable PFAS amounts in their bloodstream.

Several groups experience particularly high exposure risks:

  • Active and retired military personnel who were stationed at contaminated bases
  • Family members of veterans who lived at a contaminated base
  • Firefighters and emergency personnel using PFAS-containing foam
  • Residents living near contaminated military installations

Legal support for your PFAS-related pancreatic cancer victims

Patients and their families are faced with devastating medical, emotional, and financial challenges when diagnosed with pancreatic cancer. When PFAS exposure plays a role in your cancer development, legal action may secure essential compensation for treatment costs, lost wages, pain, and suffering.

Our experienced legal team has been helping toxic exposure victims for the past 30 years and provides complimentary case reviews. Getting an evaluation of your case is free of charge. If you wish to pursue your claim, we need your medical records confirming your pancreatic cancer diagnosis, as well as documentation of exposure to PFAS while serving in the military, working, or living near contaminated bases.