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Multiple myeloma diagnosis: Exposed to ethylene oxide?

Michael Bartlett

By Michael Bartlett

Posted on November 05th, 2025

Multiple myeloma begins its development in plasma cells from the bone marrow. When these cells are affected, they grow out of control and ultimately damage the bones, kidneys, and the immune system. Research has shown a clear connection between exposure to ethylene oxide (EtO) and an increased risk of developing multiple myeloma.

According to the Environmental Protection Agency (EPA) and the International Agency for Research on Cancer (IARC), this highly toxic gas, used in sterilization and manufacturing facilities, is a known human carcinogen. Moreover, health organizations such as the National Institute for Occupational Safety and Health (NIOSH) and the Agency for Toxic Substances and Disease Registry (ATSDR) highlight that even low-level exposure can contribute to the development of multiple myeloma over time. In essence, for individuals living close to EtO-emitting facilities, or who work in one, developing multiple myeloma is a significant risk, especially after years of inhaling contaminated air.

Prolonged exposure to EtO puts workers and nearby residents at risk for developing multiple myeloma

Multiple myeloma is usually diagnosed using blood and urine tests followed by a bone marrow biopsy. Doctors begin by investigating symptoms like persistent bone pain, fatigue, frequent infections, or unexplained fractures. A complete blood count (CBC) and tests measuring protein levels in the blood or urine can reveal abnormal antibodies that are early signs of multiple myeloma. To confirm the diagnosis, physicians take a bone marrow sample, typically extracted from the hip bone, to look for cancerous plasma cells. Further testing includes cytogenetic and molecular analysis, which helps doctors identify genetic changes that can guide treatment options and predict disease outcomes.

If you've worked in an EtO-using facility or lived near one, it's extremely important to share this information with your doctor. They will be able to connect the early symptoms of the disease to multiple myeloma and perform regular screenings to detect potential bone marrow abnormalities before they become more severe. While not everyone exposed to EtO develops multiple myeloma, the risk increases with long-term, unprotected exposure. This illness is treatable, so it's important to identify it in its early development. That's why you should track your possible exposure, stay informed, and advocate for stronger workplace and environmental protections.

ELG Law can help with your multiple myeloma claim

If you have been diagnosed with multiple myeloma and worked in a plant that uses EtO, or live in the vicinity of such a facility, you may be entitled to file a claim against the polluter responsible for your exposure. With more than 30 years of experience with toxic exposure cases, the Environmental Litigation Group can help you with all the steps leading to and throughout this process. Our team is fully aware that multiple myeloma claims require complex scientific and medical evidence, but by contacting us, you will receive a complimentary consultation to understand all your available legal options.